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Turmeric and cancer: what the evidence says

Small or mixed human studies suggest curcumin may help some chemotherapy regimens or ease treatment side effects, but controlled trials on tumors disagree and the strongest positive one used an intravenous form.

3/5 Limited

Some human evidence: small trials, trials on a related outcome, or population studies that disagree. How we score

A research summary, not a substitute for treatment. If you or someone you care for has cancer, talk to the oncologist before adding any supplement, and do not delay or replace treatment.

PubMed lists more than 10,900 papers on curcumin and cancer, almost all lab and animal work. We narrowed the search to the 438 records tagged as trials, reviews, case reports or population studies, and read 46 of the 337 human-study records (16 systematic reviews, 23 trials, 7 case reports), plus a 686-patient radiotherapy trial the search missed.

Tumor results disagree. Two breast cancer trials reported more tumor shrinkage when curcumin was added to chemotherapy (51% vs 33% with intravenous curcumin in 150 women; 38% vs 8% with oral curcumin and piperine in an unblinded trial of 120). Placebo-controlled trials in prostate cancer (50 and 97 men) and an inherited polyp condition (44 patients, 12 months) found no difference.

In a precancer of the mouth (oral leukoplakia), 3.6 g a day for 6 months shrank more lesions than placebo in 223 people (67.5% vs 55.3%), but the tissue under the microscope did not differ.

For treatment side effects, small trials point to fewer mouth sores during radiotherapy, but the largest trial, 686 women having breast radiotherapy, found no difference in skin reactions.

A 2024 critical review of 293 studies concluded that a benefit against cancer has not been convincingly shown, and that better absorption was demonstrated mainly in studies close to the companies selling the formulations. Anyone in cancer treatment should raise curcumin with their oncologist because of drug interactions (see safety notes).

The evidence ladder higher rungs count for more
  1. Meta-analyses of trialspooled randomized trials4
  2. Human studiestrials and population studies19
  3. Case reportssingle people2
  4. Animal studiesmostly rodents1
  5. Lab studiescells, test tubes15

The studies in people, read one by one

ResultTypeWhat they didWhat they found
No effectSystematic review / meta-analysis, 2024Critical analysis of 293 registered and published clinical studies of curcumin (absorption and malignant disease)
Measured: Effect on cancer treatment		Failed to convincingly show a significant positive effect on cancer therapy; better absorption was shown mainly in studies close to industry, not in independent ones. PubMed 37966571
MixedSystematic review / meta-analysis, 2025
2,580 people		Systematic review of 34 randomized trials, curcumin added to cancer treatment
Measured: Symptoms, weight, survival, progression		Heterogeneous results; significant findings mainly for mouth sores (oral mucositis) and weight loss; all trials at moderate to high risk of bias; one trial reported more vomiting. PubMed 39425780
MixedSystematic review / meta-analysis, 2021Systematic review of 314 curcumin randomized trials, focus on settings with raised cancer risk
Measured: Primary outcomes in cancer-prevention settings		23 trials were in high cancer-risk settings; 15 met all quality criteria and 10 of those were positive; few true prevention trials. PubMed 34015183
No effectSystematic review / meta-analysis, 2024Systematic review of 12 low-bias clinical trials of polyphenols in colorectal cancer
Measured: Adenomas, chemotherapy outcomes		Curcumin lowered some inflammatory markers but did not reduce intestinal adenomas or improve outcomes after chemotherapy. PubMed 39203871
PositiveRandomized trial, 2020
150 people		Double-blind placebo-controlled trial, intravenous curcumin (CUC-1, 300 mg weekly) plus paclitaxel for 12 weeks, advanced breast cancer (Armenia)
Measured: Objective tumor response (RECIST)		Response 51% vs 33% with placebo (p < 0.01) at 4 weeks of follow-up; no difference in other outcomes except less fatigue. Given by vein, not as a capsule. PubMed 32335356
PositiveRandomized trial, 2025
120 people		Randomized open-label trial, oral curcumin 1 g/day with piperine plus chemotherapy vs chemotherapy alone, advanced breast cancer (India)
Measured: Objective tumor response, PFS		Response 38.3% vs 8.3% at 4 weeks and 43.4% vs 10.6% at 12 weeks; not blinded, and the response in the chemotherapy-only group is unusually low. PubMed 40898993
No effectRandomized trial, 2021
50 people		Double-blind placebo-controlled phase II, docetaxel plus oral curcumin 6 g/day, metastatic castration-resistant prostate cancer (France)
Measured: Time to progression, PSA, survival		Progression-free survival 3.7 months with curcumin vs 5.3 with placebo (p = 0.75); no difference in PSA response or survival, despite verified absorption. PubMed 33666378
No effectRandomized trial, 2019
97 people		Double-blind placebo-controlled trial, curcumin 1,440 mg/day for 6 months during intermittent hormone therapy, prostate cancer (Korea)
Measured: Time off hormone therapy		Median off-treatment time 16.3 months vs 18.5 with placebo (p = 0.48). PubMed 30671976
No effectRandomized trial, 2018
44 people		Double-blind placebo-controlled trial, pure curcumin 3 g/day for 12 months, familial adenomatous polyposis (US, Puerto Rico)
Measured: Number and size of polyps		Mean polyps 22.6 with curcumin vs 18.6 with placebo (p = 0.58); size no different. PubMed 29802852
MixedRandomized trial, 2016
223 people		Double-blind placebo-controlled phase IIB, curcumin 3.6 g/day for 6 months, oral leukoplakia (a precancer) (India)
Measured: Lesion size, histology		Clinical response 67.5% vs 55.3% (p = 0.03); histologic response no different (HR 0.88, p = 0.71); combined response better (HR 0.50, p = 0.02). PubMed 27267893
MixedRandomized trial, 2019
28 people		Open-label randomized phase IIa, FOLFOX chemotherapy with or without oral curcumin 2 g/day, metastatic colorectal cancer (UK)
Measured: Safety, PFS, overall survival		Safe; progression-free survival not significant (HR 0.57, p = 0.2); overall survival HR 0.34 (95% CI 0.14–0.82, p = 0.02) in a 28-patient trial not designed to test survival. PubMed 31132111
No effectRandomized trial, 2021
26 people		Double-blind placebo-controlled pilot, nanocurcumin 180 mg/day during chemotherapy, muscle-invasive bladder cancer (Iran)
Measured: Complete clinical response		Complete response 50% vs 30.8% with placebo, not significant (p = 0.417). PubMed 32350847
No effectRandomized trial, 2026
53 people		Double-blind placebo-controlled phase II, 7-micronutrient mix including curcumin for 1 year with standard chemoradiation, glioblastoma (UK)
Measured: Overall survival		Median survival 14 vs 13 months (p = 0.752). A mixture, so curcumin's part cannot be isolated. PubMed 41760279
PositiveRandomized trial, 2012
36 people		Double-blind placebo-controlled crossover (4 g/day) plus open 8 g extension, MGUS and smoldering myeloma (precursors of myeloma)
Measured: Free light chains, bone turnover		Curcumin lowered free light-chain markers and a bone-resorption marker; a marker study, not a measure of progression. PubMed 22473809
MixedRandomized trial, 2026
50 people		Double-blind placebo-controlled phase IIa, Meriva 1,000 mg/day for 6 months, gastric precancerous changes (Puerto Rico, Honduras)
Measured: Stomach-lining inflammation, histology		Lower IL-1β in the stomach lining (p = 0.032); histology and DNA damage no different from placebo. PubMed 42077070
MixedClinical trial, 2008
25 people		Phase II single-arm trial, oral curcumin 8 g/day, advanced pancreatic cancer (MD Anderson)
Measured: Tumor response		2 of 21 evaluable patients showed activity (one stable over 18 months, one brief 73% regression); blood levels were low. PubMed 18628464
MixedClinical trial, 2010
17 people		Phase II single-arm trial, gemcitabine plus curcumin 8 g/day, advanced pancreatic cancer (Israel)
Measured: Response, feasibility		1 of 11 partial response, 4 stable; 5 of 17 stopped curcumin within 2 weeks for abdominal fullness or pain. PubMed 21058202
PositiveClinical trial, 2018
52 people		Phase II single-arm trial, gemcitabine plus Meriva, advanced pancreatic cancer (Italy)
Measured: Response rate		Response 27.3% and disease control 61.4%; median survival 10.2 months. No comparison group, so the effect of curcumin cannot be separated. PubMed 29614381
PositiveClinical trial, 2016
30 people		Pilot phase II single-arm trial, docetaxel plus curcumin 6 g/day, castration-resistant prostate cancer (France)
Measured: PSA and tumor response		PSA response 59%, partial response 40% of evaluable patients; the same group's later placebo-controlled trial (PMID 33666378) found no benefit. PubMed 26771576
MixedClinical trial, 2011
44 people		Phase IIa open-label trial, curcumin 2 or 4 g/day for 30 days, smokers with aberrant crypt foci (colon precancer)
Measured: Precancer markers, crypt foci number		No change in the primary prostaglandin markers; 4 g reduced aberrant crypt foci by 40%. PubMed 21372035
PositiveClinical trial, 2006
5 people		Uncontrolled case series, curcumin 480 mg plus quercetin three times daily, familial adenomatous polyposis
Measured: Polyp number and size		All 5 patients had fewer (−60.4%) and smaller (−50.9%) polyps after about 6 months; the later 44-patient randomized trial (PMID 29802852) found no effect. PubMed 16757216
PositiveCase report, 2017
1 people		Case report, myeloma approaching third relapse, daily curcumin without further treatment (UK)
Measured: Disease stability		Stable for 5 years with good quality of life. A single case cannot show the supplement caused it. PubMed 28413157
PositiveCase report, 2024
1 people		Case report, intermediate-high risk MGUS, curcumin for 16 years
Measured: Disease markers		Disease markers fell over time. A single case. PubMed 38529782
PositiveSystematic review / meta-analysis, 2025
159 people		Meta-analysis of 6 placebo-controlled trials, turmeric or curcumin (capsules, mouthwash, gel) for mouth sores during cancer treatment
Measured: Oral mucositis severity, pain, incidence		Lower mucositis scores and mouth pain than placebo; curcumin mouthwash during radiotherapy cut incidence by 37%. A side-effect outcome, not a tumor outcome. PubMed 40242451
No effectRandomized trial, 2018
686 people		Double-blind placebo-controlled multisite trial, oral curcumin 6 g/day during breast radiotherapy (US, URCC NCORP)
Measured: Radiation skin reaction severity		No reduction in radiation dermatitis severity (p = 0.552); a non-significant trend in severe cases (7.4% vs 12.9%, p = 0.082). PubMed 29192329
PositiveRandomized trial, 2014
80 people		Double-blind placebo-controlled trial, bioavailability-boosted curcuminoids 180 mg/day for 8 weeks during chemotherapy, solid tumors (Iran)
Measured: Quality of life, inflammatory markers		Quality of life improved more than placebo (p < 0.001) with lower TNF-α, TGF-β and IL-6. A side-effect outcome. PubMed 24648302

Where the sources agree, and where they don’t

2 of 7 kinds of source point toward a benefit, 3 toward no effect or harm, 2 are mixed. Agreement between independent kinds of evidence matters more than the number of papers in any one of them.

Kind of sourcePoints toDetail
Lab and animal studiesPositivemore than 10,000 papers, mostly positive
Randomized trials on tumorsMixedbreast trials positive; prostate and polyp trials null
Critical review of 293 studiesNo effectno convincing benefit shown
Registry-only resultsNo effectCLL trial: 0% response in 35 patients
Case reportsPositivemyeloma and MGUS stability, single cases
Public reportsMixed6 reports (blood cancers, prostate): 2 helped, 2 no effect, 2 unclear
FDA reportsNegativeliver reports rising; chemotherapy interaction case reports

Beyond Google: 14 findings about Turmeric from trial registries, FDA reports and patent offices that a normal search rarely shows. See them

What people report

We read public first-person posts and counted every outcome, good or bad. 6 reports about this condition, read on 2026-10-28; 0 mention side effects.

  • 2Helped
  • 2No effect
  • 0Got worse
  • 0Mixed
  • 2Too early

Why these counts prove nothing on their own: people who post are not a random sample, most take other treatments at the same time, and nobody checks the diagnosis. We show them because they tell researchers what to test next.

Read all 6 reports
  • Helped Took turmeric and ginger to thin the blood and says it seemed to help. HealthUnlocked, 2017-07 (No blood counts given.)
  • No effect Capsules for a long time and then months of a daily turmeric drink made no difference to their blood counts. HealthUnlocked, 2017-07-15 (Counts monitored by their clinic.)
  • Too early Has taken turmeric then curcumin since 2013 and is doing well on standard care without other drugs, but does not attribute it. HealthUnlocked, 2017-07 (Outcome unclear rather than early; standard care continued.)
  • Too early A daily teaspoon of turmeric for a few weeks; feels better than at any time since diagnosis with no fatigue; awaiting blood counts. HealthUnlocked, 2017-07 (Early; no counts reported.)
  • Helped Platelets slowly fell over two years on 1,000 mg curcumin with no drug change; after halving the dose they rose despite more medication. HealthUnlocked, 2017-07-16 (Poster unsure of relevance; one person’s counts.)
  • No effect Stopped and restarted curcumin around monthly PSA tests; PSA stayed at 0.05 either way. HealthUnlocked, 2022-07 (Very low PSA, near the test’s rounding limit; one person.)

Every other paper we found

PubMed returned 438 papers for this search on 2026-10-28. We read the human studies above ourselves. The rest are sorted by type automatically from PubMed's labels, which are sometimes wrong. We removed 82 papers that only share a word with this search.

Animal studies 1
  1. Pharmacokinetic interaction study of sulphasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP. Br J Pharmacol, 2012
Lab studies 15
  1. Curcumin Supplementation and Human Disease: A Scoping Review of Clinical Trials. Int J Mol Sci, 2023
  2. Comparative prevention potential of 10 mouthwashes on intolerable oral mucositis in cancer patients: A Bayesian network analysis. Oral Oncol, 2020
  3. Effectiveness of Indian Turmeric Powder with Honey as Complementary Therapy on Oral Mucositis : A Nursing Perspective among Cancer Patients in Mysore. Nurs J India, 2014
  4. Modulation of apoptosis-related cell signalling pathways by curcumin as a strategy to inhibit tumor progression. Mol Biol Rep, 2014
  5. A controlled study of a lecithinized delivery system of curcumin (Meriva®) to alleviate the adverse effects of cancer treatment. Phytother Res, 2014
  6. Spicy approach to cancer treatment. J Natl Cancer Inst, 2011
  7. Curcumin chemoprevention: the long road to clinical translation. Cancer Prev Res (Phila), 2011
  8. Curcumin, piperine could play role in preventing breast cancer. Cancer Biol Ther, 2009
  9. Heat-solubilized curcumin should be considered in clinical trials for increasing bioavailability. Clin Cancer Res, 2009
  10. Is there a role for herbal medicine in the treatment of pancreatic cancer?. Highlights from the "44th ASCO Annual Meeting". Chicago, IL, USA. May 30 - June 3, 2008. JOP, 2008
  11. Chemoprevention with special reference to inherited colorectal cancer. Fam Cancer, 2008
  12. Curcumin for chemoprevention of colon cancer. Cancer Lett, 2007
  13. New developments in the realm of complementary medicine. J Support Oncol, 2005
  14. Clinical development plan: curcumin. J Cell Biochem Suppl, 1996
  15. Strategy and planning for chemopreventive drug development: clinical development plans II. J Cell Biochem Suppl, 1996
Reviews 85
  1. Case study, clinical trials, critical analysis and mechanistic overview of conventional and resistant breast cancer treatment using functionalized albumin nanoparticles: a comprehensive review. Biochem Biophys Res Commun, 2026
  2. Randomized Controlled Trials for Oral Leukoplakia. Oral Dis, 2025
  3. Is Curcumin Intake Really Effective for Chronic Inflammatory Metabolic Disease? A Review of Meta-Analyses of Randomized Controlled Trials. Nutrients, 2024
  4. Curcumin in Cancer Prevention: Insights from Clinical Trials and Strategies to Enhance Bioavailability. Curr Pharm Des, 2024
  5. Promising Approaches in Plant-Based Therapies for Thyroid Cancer: An Overview of In Vitro, In Vivo, and Clinical Trial Studies. Int J Mol Sci, 2024
  6. Targeting CTGF in Cancer: An Emerging Therapeutic Opportunity. Trends Cancer, 2021
  7. Implementing Curcumin in Translational Oncology Research. Molecules, 2020
  8. Dietary Factors and Supplements Influencing Prostate Specific-Antigen (PSA) Concentrations in Men with Prostate Cancer and Increased Cancer Risk: An Evidence Analysis Review Based on Randomized Controlled Trials. Nutrients, 2020
  9. Obstacles against the Marketing of Curcumin as a Drug. Int J Mol Sci, 2020
  10. Nutritional traditional and complementary medicine strategies in pediatric cancer: A narrative review. Pediatr Blood Cancer, 2020
  11. Plant natural products with anti-thyroid cancer activity. Fitoterapia, 2020
  12. Mechanism of Anti-Cancer Activity of Curcumin on Androgen-Dependent and Androgen-Independent Prostate Cancer. Nutrients, 2020
  13. Mechanistic Understanding of Curcumin's Therapeutic Effects in Lung Cancer. Nutrients, 2019
  14. Activators and Inhibitors of NRF2: A Review of Their Potential for Clinical Development. Oxid Med Cell Longev, 2019
  15. Is curcumin bioavailability a problem in humans: lessons from clinical trials. Expert Opin Drug Metab Toxicol, 2019
  16. Curcumin Combination Chemotherapy: The Implication and Efficacy in Cancer. Molecules, 2019
  17. Medicinal plants and their isolated phytochemicals for the management of chemotherapy-induced neuropathy: therapeutic targets and clinical perspective. Daru, 2019
  18. Inflammation, a Double-Edge Sword for Cancer and Other Age-Related Diseases. Front Immunol, 2018
  19. Curcumin as a therapeutic agent for blocking NF-κB activation in ulcerative colitis. Immunopharmacol Immunotoxicol, 2018
  20. Therapeutic Potential and Recent Advances of Curcumin in the Treatment of Aging-Associated Diseases. Molecules, 2018
  21. Plant Secondary Metabolites as Anticancer Agents: Successes in Clinical Trials and Therapeutic Application. Int J Mol Sci, 2018
  22. Protective Effects of Indian Spice Curcumin Against Amyloid-β in Alzheimer's Disease. J Alzheimers Dis, 2018
  23. Could Aspirin and Diets High in Fiber Act Synergistically to Reduce the Risk of Colon Cancer in Humans? Int J Mol Sci, 2018
  24. MicroRNA: A novel target of curcumin in cancer therapy. J Cell Physiol, 2018
  25. Curcumin mediates anticancer effects by modulating multiple cell signaling pathways. Clin Sci (Lond), 2017
  26. Curcumin Nanotechnologies and Its Anticancer Activity. Nutr Cancer, 2017
  27. Curcumin inhibits cancer progression through regulating expression of microRNAs. Tumour Biol, 2017
  28. Therapeutic Potential of Curcumin in Treatment of Pancreatic Cancer: Current Status and Future Perspectives. J Cell Biochem, 2017
  29. Anticancer Activity of Curcumin and Its Analogues: Preclinical and Clinical Studies. Cancer Invest, 2017
  30. Therapeutic Potential of Curcumin for the Treatment of Brain Tumors. Oxid Med Cell Longev, 2016
  31. Cell death mechanisms of plant-derived anticancer drugs: beyond apoptosis. Apoptosis, 2015
  32. Dietary phenolics against colorectal cancer--From promising preclinical results to poor translation into clinical trials: Pitfalls and future needs. Mol Nutr Food Res, 2015
  33. Breast cancer resistance protein (ABCG2) in clinical pharmacokinetics and drug interactions: practical recommendations for clinical victim and perpetrator drug-drug interaction study design. Drug Metab Dispos, 2015
  34. Curcumin and inflammatory bowel disease: potential and limits of innovative treatments. Molecules, 2014
  35. Potential application of curcumin and its analogues in the treatment strategy of patients with primary epithelial ovarian cancer. Int J Mol Sci, 2014
  36. The role of phytochemicals as micronutrients in health and disease. Curr Opin Clin Nutr Metab Care, 2014
  37. Molecular mechanism of TGF-β signaling pathway in colon carcinogenesis and status of curcumin as chemopreventive strategy. Tumour Biol, 2014
  38. Recent progress on nutraceutical research in prostate cancer. Cancer Metastasis Rev, 2014
  39. Novel insights of dietary polyphenols and obesity. J Nutr Biochem, 2014
  40. Curcumin-free turmeric exhibits anti-inflammatory and anticancer activities: Identification of novel components of turmeric. Mol Nutr Food Res, 2013
  41. Curcumin, a potential therapeutic candidate for retinal diseases. Mol Nutr Food Res, 2013
  42. Curcumin, a component of turmeric: from farm to pharmacy. Biofactors, 2013
  43. Therapeutic roles of curcumin: lessons learned from clinical trials. AAPS J, 2013
  44. Advances in clinical study of curcumin. Curr Pharm Des, 2013
  45. Multitargeting by turmeric, the golden spice: From kitchen to clinic. Mol Nutr Food Res, 2013
  46. Discovery of curcumin, a component of golden spice, and its miraculous biological activities. Clin Exp Pharmacol Physiol, 2012
  47. Curcumin and its formulations: potential anti-cancer agents. Anticancer Agents Med Chem, 2012
  48. Curcuma as a functional food in the control of cancer and inflammation. Curr Opin Clin Nutr Metab Care, 2011
  49. Neuroprotection by spice-derived nutraceuticals: you are what you eat! Mol Neurobiol, 2011
  50. Modulation of glioma risk and progression by dietary nutrients and antiinflammatory agents. Nutr Cancer, 2011
  51. Targeting cell signaling and apoptotic pathways by dietary agents: role in the prevention and treatment of cancer. Nutr Cancer, 2011
  52. Potential of the dietary antioxidants resveratrol and curcumin in prevention and treatment of hematologic malignancies. Molecules, 2010
  53. Colorectal cancer: chemopreventive role of curcumin and resveratrol. Nutr Cancer, 2010
  54. Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs. Nutr Cancer, 2010
  55. Updates of mTOR inhibitors. Anticancer Agents Med Chem, 2010
  56. Curcumin in cancer chemoprevention: molecular targets, pharmacokinetics, bioavailability, and clinical trials. Arch Pharm (Weinheim), 2010
  57. Curcumin as a therapeutic agent: the evidence from in vitro, animal and human studies. Br J Nutr, 2010
  58. Apoptosis by dietary agents for prevention and treatment of prostate cancer. Endocr Relat Cancer, 2010
  59. Gonadotropin-releasing hormone/human chorionic gonadotropin beta based recombinant antibodies and vaccines. J Reprod Immunol, 2009
  60. Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research. Altern Med Rev, 2009
  61. Clinical development of novel proteasome inhibitors for cancer treatment. Expert Opin Investig Drugs, 2009
  62. Histone acetyltransferase inhibitors and preclinical studies. Expert Opin Ther Pat, 2009
  63. New mechanisms and therapeutic potential of curcumin for colorectal cancer. Mol Nutr Food Res, 2008
  64. Natural compounds with proteasome inhibitory activity for cancer prevention and treatment. Curr Protein Pept Sci, 2008
  65. Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins. Cancer Lett, 2008
  66. Curcumin: from ancient medicine to current clinical trials. Cell Mol Life Sci, 2008
  67. Treatment of inflammatory bowel disease: a review of medical therapy. World J Gastroenterol, 2008
  68. Curcumin in cancer management: recent results of analogue design and clinical studies and desirable future research. Mol Nutr Food Res, 2008
  69. Curcumin as "Curecumin": from kitchen to clinic. Biochem Pharmacol, 2008
  70. Moving toward bioadjuvant approaches to head and neck cancer prevention. Int J Radiat Oncol Biol Phys, 2007
  71. Role of curcumin in cancer therapy. Curr Probl Cancer, 2007
  72. Strategies for colon cancer prevention: combination of chemopreventive agents. Subcell Biochem, 2007
  73. Clinical studies with curcumin. Adv Exp Med Biol, 2007
  74. Review. Facts and fiction of phytotherapy for prostate cancer: a critical assessment of preclinical and clinical data. In Vivo, 2007
  75. Dietary polyphenolic phytochemicals--promising cancer chemopreventive agents in humans? A review of their clinical properties. Int J Cancer, 2007
  76. The proteasome as a potential target for novel anticancer drugs and chemosensitizers. Drug Resist Updat, 2006
  77. Clinical trials of natural products as chemopreventive agents for prostate cancer. Expert Opin Investig Drugs, 2006
  78. Polyphenolic phytochemicals versus non-steroidal anti-inflammatory drugs: which are better cancer chemopreventive agents? J Chemother, 2004
  79. Chemical genetics for therapeutic target mining. Expert Opin Ther Targets, 2004
  80. Anticancer potential of curcumin: preclinical and clinical studies. Anticancer Res, 2003
  81. Turmeric. Am J Health Syst Pharm, 2000
  82. Suppression of tumour development by substances derived from the diet--mechanisms and clinical implications. Br J Clin Pharmacol, 1998
  83. Biomarker end-points in cancer chemoprevention trials. IARC Sci Publ, 1997
  84. New agents for cancer chemoprevention. J Cell Biochem Suppl, 1996
  85. Chemopreventive drug development: perspectives and progress. Cancer Epidemiol Biomarkers Prev, 1994
Other papers, not yet read by us 231
  1. Curcumin in ovarian cancer: mechanistic insights and translational potential. Med Oncol, 2026
  2. Precision medicine directed therapy enabling long-term survival in medulloblastoma: a case report. Front Oncol, 2026
  3. Autophagy potential of polyphenols in breast carcinoma: A systematic review. Pathol Res Pract, 2026
  4. The potential value of curcumin in breast cancer: a systematic review and meta-analysis of preclinical studies. Front Pharmacol, 2026
  5. Advancing Gastric Cancer Chemoprevention: Early Signals and Ongoing Challenges. Cancer Prev Res (Phila), 2026
  6. The Role of Anthocyanins, Curcumin, and Resveratrol in the Prevention and Management of Metabolic Disorders: A Systematic Review. Molecules, 2026
  7. Turmeric: A Comprehensive Review of Its Botany, Traditional Uses, Phytochemistry, and Mechanisms as a Functional Food. Nutrients, 2026
  8. Preclinical and Clinical Evidence on the Efficacy and Cytotoxicity of Curcumin and Curcumin Derivatives in Chronic Myeloid Leukemia: A Systematic Review. Phytochem Anal, 2026
  9. Effect of curcumin intervention on radiation-induced injury: a GRADE-based systematic review and meta-analysis. BMC Cancer, 2026
  10. Pharmacological effects and mechanisms of curcumin in animal models of Parkinson's disease: a systematic review and meta-analysis. Front Pharmacol, 2026
  11. Role of curcumin and its nanoformulations in the management of oral squamous cell carcinoma: A systematic review. Dent Med Probl, 2026
  12. A Systematic Review of Turmeric/Curcumin for Prevention and Treatment of Oral Mucositis Due to Radiotherapy and/or Chemotherapy for Head and Neck Cancer. J Integr Complement Med, 2026
  13. Assessing Nutraceuticals for Hepatic Steatosis: A Standardized In Vitro Approach. Nutrients, 2026
  14. An Updated Insight into the Phytomolecules Reported for the Treatment of Colon Cancer from 2015 to 2024: Systematic Review. Anticancer Agents Med Chem, 2026
  15. Novel immune-modulating formula versus standard formula for gastrointestinal cancer patients at risk of malnutrition undergoing surgery: A pilot randomized controlled trial. Clin Nutr ESPEN, 2026
  16. High-fat Diet-associated Digestive Cancers: Mechanisms, Natural Product-based Therapies, and Drug Development. Phytomedicine, 2026
  17. [Therapeutic potential of curcumin in colorectal cancer ‒ A systematic review]. Nutr Hosp, 2026
  18. Comparative Efficacy of Medical Therapies in Reducing the Risk of Postoperative Recurrence in Crohn's Disease: A Systematic Review and Network Meta-Analysis. Inflamm Bowel Dis, 2026
  19. Benefits of Nanocurcumin on Mortality in Patients with COVID-19: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. J Integr Complement Med, 2026
  20. Effectiveness and mechanisms of curcumin for colorectal cancer in preclinical models:A systematic review and meta-analysis. J Ethnopharmacol, 2026
  21. Advances in Radiation Therapy Enhancement and Radio-Protection By Nano-Curcumins: A Systematic Review. Curr Cancer Drug Targets, 2026
  22. Exploring the In Vitro Anticancer Potential of Indonesian Medicinal Plants and Natural Compounds for Breast Cancer Therapy. Asian Pac J Cancer Prev, 2025
  23. Systematic review and network meta-analysis of the effects of plant active substance on quality of life in breast cancer patients. Front Pharmacol, 2025
  24. Efficacy of curcumin/turmeric on inflammation and oxidative stress in prediabetes and type 2 diabetes: a systematic review and dose-response meta-analysis. Inflammopharmacology, 2025
  25. Curcumin in prostate cancer: a systematic review of molecular mechanisms and nanoformulated therapeutic strategies. BMC Cancer, 2025
  26. Chitosan-Based Systems for Curcumin Delivery: Evidence for Therapeutic Applications. J Biochem Mol Toxicol, 2025
  27. A Systematic Review of Food-Derived DNA Methyltransferase Modulators: Mechanistic Insights and Perspectives for Healthy Aging. Adv Nutr, 2025
  28. Investigating the Potential of Curcumin in the Treatment of Nonsmall Cell Lung Cancer: A Systematic Review With Meta-Analysis, Network Pharmacology, and Mendelian Randomization. Phytother Res, 2025
  29. Bioelectrical Impedance Assessment in a Patient with Breast Cancer: A Case Report on the Effect of Integrative Therapies on Cellular Homeostasis. Nutrients, 2025
  30. The influence of antioxidant supplementation on adverse effects and tumor interaction during radiotherapy: a systematic review. Clin Exp Med, 2025
  31. Curcumin as a therapeutic agent in liver cancer: a systematic review of preclinical models and mechanisms. Eur J Med Res, 2025
  32. The effectiveness of nutritional supplements in improving polycystic ovary syndrome in women: a systematic review and network meta-analysis. Reprod Biol Endocrinol, 2025
  33. Impact of Dietary Supplements on Clinical Outcomes and Quality of Life in Patients with Breast Cancer: A Systematic Review. Nutrients, 2025
  34. Research trajectory and future trends in curcumin related to immunity: a bibliometric analysis of publications from last two decades. Front Immunol, 2025
  35. Topical Curcumin for Prevention of Radiation-Induced Dermatitis: A Pilot Double‑Blind, Placebo‑Controlled Trial. Cancer Invest, 2025
  36. Nanoparticle-based delivery systems for phytochemicals in cancer therapy: molecular mechanisms, clinical evidence, and emerging trends. Drug Dev Ind Pharm, 2025
  37. The effect of oral curcumin on vincristine-induced neuropathy in pediatric acute lymphoblastic leukemia: A double-blind randomized controlled clinical trial. BMC Cancer, 2025
  38. Curcumin Supplementation as a Preventive Strategy Against Tamoxifen-Induced Nonalcoholic Fatty Liver Disease in ER+ Breast Cancer Patients: A Triple-Blind Randomized Placebo-Controlled Trial. J Diet Suppl, 2025
  39. Comparative evaluation of the efficacy of herbal and benzydamine mouthwashes in preventing radiation-induced oral mucositis among head and neck cancer patients: a systematic review and network meta-analysis. Evid Based Dent, 2025
  40. Effects of nanocurcumin supplementation on metabolic syndrome: A systematic review and meta-analysis of randomized controlled trials. Pharmacol Res, 2025
  41. Effect of curcumin on lipid mediators, glycemic index, and oxidative stress and inflammation biomarkers in polycystic ovary syndrome: Future directions and current knowledge - A systematic review. Prostaglandins Other Lipid Mediat, 2025
  42. Efficacy and safety of dietary polyphenol administration as assessed by hormonal, glycolipid metabolism, inflammation and oxidative stress parameters in patients with PCOS: a meta-analysis and systematic review. Crit Rev Food Sci Nutr, 2025
  43. The Potential Role of Curcumin as a Regulator of microRNA in Colorectal Cancer: A Systematic Review. Microrna, 2025
  44. Systematic Review and Meta-analysis Indicating Curcumin to Enhance the Synergistic Potential of Paclitaxel and Reduce Cell Viability, Tumor Volume, and Drug Resistance in Different Cancers. Curr Med Chem, 2025
  45. "The protective effect of nano curcumin supplementation on doxorubicin induced cardiotoxicity in breast cancer patients; a randomized, double-blind clinical trial". J Oncol Pharm Pract, 2025
  46. Current evidence and future direction on evaluating the anticancer effects of curcumin, gingerols, and shogaols in cervical cancer: A systematic review. PLoS One, 2024
  47. Evaluating the efficacy of curcumin in the management of oral potentially malignant disorders: a systematic review and meta-analysis. PeerJ, 2024
  48. A comprehensive and systematic review on Curcumin as a promising candidate for the inhibition of melanoma growth: From pre-clinical evidence to molecular mechanisms of action. Phytomedicine, 2024
  49. The Association Between Anti-Neoplastic Effects of Curcumin and Urogenital Cancers: A Systematic Review. Biomed Res Int, 2024
  50. Clinical Assessment of Breast Cancer Resistance Protein (BCRP)-Mediated Drug-Drug Interactions of Sepiapterin with Curcumin and Rosuvastatin in Healthy Volunteers. Drugs R D, 2024
  51. Oral mucositis management with photobiomodulation, Bidens pilosa L. (Asteraceae) and Curcuma longa L. (Zingiberaceae), the FITOPROT herbal medicine, and its influence on inflammatory cytokine levels: a randomized clinical trial. Support Care Cancer, 2024
  52. Establishment of a Mesoamerican-Caribbean South-South Research Platform: Challenges in the Meriva (Curcuminoids) Gastric Cancer Chemoprevention Trial. Cancer Prev Res (Phila), 2024
  53. The Efficacy of Curcumin Application to Melanoma in Mice: A Systematic Review and Meta-analysis. Ann Plast Surg, 2024
  54. Is oral nano-curcumin formulation a safe and effective measure for preventing cisplatin-induced nephrotoxicity in cancer patients? Anticancer Drugs, 2024
  55. The effects of curcumin supplementation on biomarkers of inflammation, oxidative stress, and endothelial function: A meta-analysis of meta-analyses. Prostaglandins Other Lipid Mediat, 2024
  56. Two by Two Factorial Design using Metformin and Curcumin for Second Primary Head and Neck Cancer Prevention Trial. Asian Pac J Cancer Prev, 2024
  57. Application and potential value of curcumin in prostate cancer: a meta-analysis based on animal models. Front Pharmacol, 2024
  58. The intervention of curcumin on rodent models of hepatic fibrosis: A systematic review and meta-analysis. PLoS One, 2024
  59. A comprehensive review of phytoconstituents in liver cancer prevention and treatment: targeting insights into molecular signaling pathways. Med Oncol, 2024
  60. Efficacy of turmeric in the treatment of oral mucositis in patients with head and neck cancer after radiotherapy or chemoradiotherapy: a systematic review and meta-analysis. Front Pharmacol, 2024
  61. Randomized placebo-controlled, double-blind clinical trial of nanoemulsion curcumin in women with aromatase inhibitor-induced arthropathy: an Alliance/NCORP pilot trial. Breast Cancer Res Treat, 2024
  62. Curcumin effects on glycaemic indices, lipid profile, blood pressure, inflammatory markers and anthropometric measurements of non-alcoholic fatty liver disease patients: A systematic review and meta-analysis of randomized clinical trials. Complement Ther Med, 2024
  63. Artificial and natural interventions for chemotherapy- and / or radiotherapy-induced cognitive impairment: A systematic review of animal studies. Neurosci Biobehav Rev, 2024
  64. Immunomodulation with AM3 and antioxidants creates an adequate framework for skin repair and decreases the monocyte proinflammatory stage in smoker women. Biomed Pharmacother, 2024
  65. Polyphenol Supplementation Enhances the Efficacy of PD-1/PD-L1 Inhibitors Against Cancer: A Meta-Analysis of Animal Studies. Nutr Cancer, 2024
  66. Effects of curcumin and ursolic acid in prostate cancer: A systematic review. Urologia, 2024
  67. Inflammatory and Metabolic Biomarker Assessment in a Randomized Presurgical Trial of Curcumin and Anthocyanin Supplements in Patients with Colorectal Adenomas. Nutrients, 2023
  68. Effects of a mucoadhesive phytomedicine (Curcuma longa L. and Bidens pilosa L.) on radiotherapy-induced oral mucositis and quality of life of patients undergoing head and neck cancer treatment: randomized clinical trial. Support Care Cancer, 2023
  69. Effects of dietary polyphenol curcumin supplementation on metabolic, inflammatory, and oxidative stress indices in patients with metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials. Front Endocrinol (Lausanne), 2023
  70. Modulation of carcinogenesis with selected GRAS nutraceuticals via Keap1-Nrf2 signaling pathway. Phytother Res, 2023
  71. Effectiveness of natural-based products for radiation-induced oral mucositis therapy: A systematic review. Cancer Treat Res Commun, 2023
  72. Combination Chemotherapy with Selected Polyphenols in Preclinical and Clinical Studies-An Update Overview. Molecules, 2023
  73. Efficacy of curcumin for amelioration of radiotherapy-induced oral mucositis: a preliminary randomized controlled clinical trial. BMC Cancer, 2023
  74. Effects of oral supplementation to manage radiation dermatitis in cancer patients: a systematic review. Support Care Cancer, 2023
  75. Impact of Curcumin Supplementation on Radiation Dermatitis Severity: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Asian Pac J Cancer Prev, 2023
  76. Therapeutic effect of turmeric on radiodermatitis: A systematic review. Physiol Rep, 2023
  77. The impact of curcumin supplementation on systemic lupus erythematosus and lupus nephritis: A systematic review. Lupus, 2023
  78. Natural and miscellaneous agents for the prevention of acute radiation dermatitis: a systematic review and meta-analysis. Support Care Cancer, 2023
  79. Antioxidant and anti-inflammatory effects of curcumin/turmeric supplementation in adults: A GRADE-assessed systematic review and dose-response meta-analysis of randomized controlled trials. Cytokine, 2023
  80. The effectiveness of nano-curcumin on patients with COVID-19: A systematic review of clinical trials. Phytother Res, 2023
  81. Nutritional interventions for the prevention and treatment of cancer therapy-induced oral mucositis: an umbrella review of systematic reviews and meta-analysis. Nutr Rev, 2023
  82. Complementary administration of curcumin in PCOS: a systematic review. Minerva Obstet Gynecol, 2023
  83. Effects of nutrition on metabolic and endocrine outcomes in women with polycystic ovary syndrome: an umbrella review of meta-analyses of randomized controlled trials. Nutr Rev, 2023
  84. Randomized Control Study of the Effects of Turmeric Mouthwash on Oral Health Status, Treatment-Induced Mucositis, and Associated Oral Dysfunctions Among Patients With Head and Neck Cancer. Cancer Nurs, 2023
  85. Pembrolizumab, radiotherapy, and an immunomodulatory five-drug cocktail in pretreated patients with persistent, recurrent, or metastatic cervical or endometrial carcinoma: Results of the phase II PRIMMO study. Cancer Immunol Immunother, 2023
  86. The Role of Herbal Medicine in Cholangiocarcinoma Control: A Systematic Review. Planta Med, 2023
  87. Efficacy of Wholistic Turmeric Supplement on Adenomatous Polyps in Patients with Familial Adenomatous Polyposis-A Randomized, Double-Blinded, Placebo-Controlled Study. Genes (Basel), 2022
  88. Therapeutic effect and safety of curcumin in women with PCOS: A systematic review and meta-analysis. Front Endocrinol (Lausanne), 2022
  89. Synergistically Anti-Multiple Myeloma Effects: Flavonoid, Non-Flavonoid Polyphenols, and Bortezomib. Biomolecules, 2022
  90. The effects of curcumin-containing supplements on inflammatory biomarkers in hemodialysis patients: A systematic review and meta-analysis. Phytother Res, 2022
  91. Multifunctionality of Calebin A in inflammation, chronic diseases and cancer. Front Oncol, 2022
  92. The melanin inhibitory effect of plants and phytochemicals: A systematic review. Phytomedicine, 2022
  93. Efficacy and safety of curcumin in psoriasis: preclinical and clinical evidence and possible mechanisms. Front Pharmacol, 2022
  94. A Double-Blind, Placebo-Controlled Randomized Phase IIa Study: Evaluating the Effect of Curcumin for Treatment of Cancer Anorexia-Cachexia Syndrome in Solid Cancer Patients. Asian Pac J Cancer Prev, 2022
  95. Research Status and Hotspots of Anticancer Natural Products Based on the Patent Literature and Scientific Articles. Front Pharmacol, 2022
  96. Preclinical studies of the antitumor effect of curcumin-loaded polymeric nanocapsules: A systematic review and meta-analysis. Phytother Res, 2022
  97. Effect of Nano-Curcumin on Radiotherapy-Induced Skin Reaction in Breast Cancer Patients: A Randomized, Triple-Blind, Placebo-Controlled Trial. Curr Radiopharm, 2022
  98. Long-term Survival, Tolerability, and Safety of First-Line Bevacizumab and FOLFIRI in Combination With Ginsenoside-Modified Nanostructured Lipid Carrier Containing Curcumin in Patients With Unresectable Metastatic Colorectal Cancer. Integr Cancer Ther, 2022
  99. Efficacy of oral and topical antioxidants in the prevention and management of oral mucositis in head and neck cancer patients: a systematic review and meta-analyses. Support Care Cancer, 2022
  100. The effects of curcumin-containing supplementations on inflammatory markers and lipid profiles in patients with chronic kidney diseases: a systematic review and meta-analysis of randomized controlled trials. J Complement Integr Med, 2022
  101. Effects of dietary polyphenols in the glycemic, renal, inflammatory, and oxidative stress biomarkers in diabetic nephropathy: a systematic review with meta-analysis of randomized controlled trials. Nutr Rev, 2022
  102. The effect of curcumin supplementation on delayed-onset muscle soreness, inflammation, muscle strength, and joint flexibility: A systematic review and dose-response meta-analysis of randomized controlled trials. Phytother Res, 2022
  103. A Systematic Review of Nonclinical Studies on the Effect of Curcumin in Chemotherapy- induced Cardiotoxicity. Curr Pharm Des, 2022
  104. Combination of Curcumin and Photodynamic Therapy Based on the Use of Red Light or Near-Infrared Radiation in Cancer: A Systematic Review. Anticancer Agents Med Chem, 2022
  105. Topical henna and curcumin (Alpha®) ointment efficacy for prevention of capecitabine induced hand-foot syndrome: A randomized, triple-blinded, placebo-controlled clinical. Daru, 2022
  106. A Systematic Review on Curcumin and Anti-Plasmodium berghei Effects. Curr Drug Discov Technol, 2022
  107. A phase I evaluation of the effect of curcumin on dose-limiting toxicity and pharmacokinetics of irinotecan in participants with solid tumors. Clin Transl Sci, 2022
  108. Curcumin and Polycystic Ovary Syndrome: a Systematic Review. Reprod Sci, 2022
  109. Treatment of glioblastoma with re-purposed renin-angiotensin system modulators: Results of a phase I clinical trial. J Clin Neurosci, 2022
  110. Effect of Curcumin on Glycaemic and Lipid Parameters in Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Reprod Sci, 2022
  111. The effects of curcumin as dietary supplement for patients with polycystic ovary syndrome: An updated systematic review and meta-analysis of randomized clinical trials. Phytother Res, 2022
  112. Testing the Anti-inflammatory Effects of Curcuminoids in Patients with Colorectal Cancer. Methods Mol Biol, 2022
  113. A Randomized, Placebo-Controlled Study to Evaluate the Effect of Bio-Enhanced Turmeric Formulation on Radiation-Induced Oral Mucositis. ORL J Otorhinolaryngol Relat Spec, 2022
  114. The Effects of Curcumin on the Side Effects of Anticancer Drugs in Chemotherapy: A Randomized Controlled Trial. Adv Exp Med Biol, 2021
  115. Effects of Curcuminoids on Systemic Inflammation and Quality of Life in Patients with Colorectal Cancer Undergoing Chemotherapy: A Randomized Controlled Trial. Adv Exp Med Biol, 2021
  116. Curcumin supplementation improves biomarkers of oxidative stress and inflammation in conditions of obesity, type 2 diabetes and NAFLD: updating the status of clinical evidence. Food Funct, 2021
  117. Effects of Zeolite as a Drug Delivery System on Cancer Therapy: A Systematic Review. Molecules, 2021
  118. Safety and efficacy of a mucoadhesive phytomedication containing curcuminoids and Bidens pilosa L. extract in the prevention and treatment of radiochemotherapy-induced oral mucositis: Triple-blind, randomized, placebo-controlled, clinical trial. Head Neck, 2021
  119. A Comparative Study to Evaluate the Efficacy of Curcumin Lozenges (TurmNova®) and Intralesional Corticosteroids with Hyaluronidase in Management of Oral Submucous Fibrosis. J Contemp Dent Pract, 2021
  120. Effects of nanomicelle curcumin capsules on prevention and treatment of oral mucosits in patients under chemotherapy with or without head and neck radiotherapy: a randomized clinical trial. BMC Complement Med Ther, 2021
  121. Newly Developed Highly Bioavailable Curcumin Formulation, curcuRougeTM, Reduces Neutrophil/Lymphocyte Ratio in the Elderly: A Double-Blind, Placebo-Controlled Clinical Trial. J Nutr Sci Vitaminol (Tokyo), 2021
  122. Anti-inflammatory effects of oral supplementation with curcumin: a systematic review and meta-analysis of randomized controlled trials. Nutr Rev, 2021
  123. Curcumin for the Treatment of Prostate Diseases: A Systematic Review of Controlled Clinical Trials. Adv Exp Med Biol, 2021
  124. Molecular mechanisms underlying curcumin-mediated microRNA regulation in carcinogenesis; Focused on gastrointestinal cancers. Biomed Pharmacother, 2021
  125. A Systematic Review and Meta-Analysis on the Efficacy of Curcumin/Turmeric for the Prevention and Amelioration of Radiotherapy/Radiochemotherapy Induced Oral Mucositis in Head and Neck Cancer Patients. Asian Pac J Cancer Prev, 2021
  126. Prolonged Neutropenia and Yellowish Discoloration of the Skin, But Not the Sclera, Following Excessive Turmeric Raw Root Ingestion. Cureus, 2021
  127. Pharmaceuticals targeting signaling pathways of endometriosis as potential new medical treatment: A review. Med Res Rev, 2021
  128. Disposition of Dietary Polyphenols in Breast Cancer Patients' Tumors, and Their Associated Anticancer Activity: The Particular Case of Curcumin. Mol Nutr Food Res, 2021
  129. Effect of curcumin on proinflammatory cytokines: A meta-analysis of randomized controlled trials. Cytokine, 2021
  130. Study protocol of a phase 1 clinical trial establishing the safety of intrapleural administration of liposomal curcumin: curcumin as a palliative treatment for malignant pleural effusion (IPAL-MPE). BMJ Open, 2021
  131. In Vivo Efficacy and Toxicity of Curcumin Nanoparticles in Breast Cancer Treatment: A Systematic Review. Front Oncol, 2021
  132. Effects of Curcumin on Glycemic Control and Lipid Profile in Polycystic Ovary Syndrome: Systematic Review with Meta-Analysis and Trial Sequential Analysis. Nutrients, 2021
  133. Analysis of Curcumin as a Radiosensitizer in Cancer Therapy with Serum Survivin Examination: Randomised Control Trial. Asian Pac J Cancer Prev, 2021
  134. Effects of the Use of Curcumin on Ulcerative Colitis and Crohn's Disease: A Systematic Review. J Med Food, 2021
  135. RENISUS Plants and Their Potential Antitumor Effects in Clinical Trials and Registered Patents. Nutr Cancer, 2021
  136. The Role of the Curcumin for Inducing Apoptosis in Acute Lymphoblastic Leukemia Cells: A Systematic Review. Nutr Cancer, 2021
  137. Prophylactic and Therapeutic Effects of Curcumin on Treatment-Induced Oral Mucositis in Patients with Head and Neck Cancer: A Meta-Analysis of Randomized Controlled Trials. Nutr Cancer, 2021
  138. Effectiveness of curcumin mouthwash on radiation-induced oral mucositis among head and neck cancer patients: A triple-blind, pilot randomised controlled trial. Indian J Dent Res, 2020
  139. Radiodermatitis in Patients With Cancer: Systematic Review and Meta-Analysis. Oncol Nurs Forum, 2020
  140. Clinical effects of curcumin in enhancing cancer therapy: A systematic review. BMC Cancer, 2020
  141. Dietary Phenolics against Breast Cancer. A Critical Evidence-Based Review and Future Perspectives. Int J Mol Sci, 2020
  142. Chemopreventive Synergism between Green Tea Extract and Curcumin in Patients with Potentially Malignant Oral Disorders: A Double-blind, Randomized Preliminary Study. J Contemp Dent Pract, 2020
  143. The role of curcumin/curcuminoids during gastric cancer chemotherapy: A systematic review of non-clinical study. Life Sci, 2020
  144. The Effect of Theracurmin on Cognitive Function in an Older Patient with Chemobrain. Clin Interv Aging, 2020
  145. A Review of Cytotoxic Plants of the Indian Subcontinent and a Broad-Spectrum Analysis of Their Bioactive Compounds. Molecules, 2020
  146. A randomized, phase 1, placebo-controlled trial of APG-157 in oral cancer demonstrates systemic absorption and an inhibitory effect on cytokines and tumor-associated microbes. Cancer, 2020
  147. Curcumin: From a controversial "panacea" to effective antineoplastic products. Medicine (Baltimore), 2020
  148. Utility of topical agents for radiation dermatitis and pain: a randomized clinical trial. Support Care Cancer, 2020
  149. Oncogenesis and Tumor Inhibition by MicroRNAs and its Potential Therapeutic Applications: A Systematic Review. Microrna, 2020
  150. Modulation of regulatory T cells by natural products in cancer. Cancer Lett, 2019
  151. PRIMMO study protocol: a phase II study combining PD-1 blockade, radiation and immunomodulation to tackle cervical and uterine cancer. BMC Cancer, 2019
  152. Photobiomodulation Therapy in Cancer Patients with Mucositis: A Clinical Evaluation. Photobiomodul Photomed Laser Surg, 2019
  153. Curcumin: Total-Scale Analysis of the Scientific Literature. Molecules, 2019
  154. Effects of turmeric and curcumin on oral mucositis: A systematic review. Phytother Res, 2019
  155. Oral administration of nanomicelle curcumin in the prevention of radiotherapy-induced mucositis in head and neck cancers. Spec Care Dentist, 2019
  156. Efficacy of curcumin for management of oral submucous fibrosis: a systematic review of randomized clinical trials. Oral Surg Oral Med Oral Pathol Oral Radiol, 2019
  157. A systematic review of herbal medicines for the treatment of cancer cachexia in animal models. J Zhejiang Univ Sci B, 2019
  158. Randomized, double-blind, placebo-controlled phase II trial of nanocurcumin in prostate cancer patients undergoing radiotherapy. Phytother Res, 2019
  159. The effects of curcumin-containing supplements on biomarkers of inflammation and oxidative stress: A systematic review and meta-analysis of randomized controlled trials. Phytother Res, 2019
  160. A combination of hydroxytyrosol, omega-3 fatty acids and curcumin improves pain and inflammation among early stage breast cancer patients receiving adjuvant hormonal therapy: results of a pilot study. Clin Transl Oncol, 2019
  161. Reducing postsurgical exudate in breast cancer patients by using San Huang decoction to ameliorate inflammatory status: a prospective clinical trial. Curr Oncol, 2018
  162. Prevention from radiation damage by natural products. Phytomedicine, 2018
  163. A phase 1 dose-escalation study on the safety, tolerability and activity of liposomal curcumin (Lipocurc™) in patients with locally advanced or metastatic cancer. Cancer Chemother Pharmacol, 2018
  164. Randomized clinical trial of a mucoadhesive formulation containing curcuminoids (Zingiberaceae) and Bidens pilosa Linn (Asteraceae) extract (FITOPROT) for prevention and treatment of oral mucositis - phase I study. Chem Biol Interact, 2018
  165. Curcumin induces endoplasmic reticulum stress-associated apoptosis in human papillary thyroid carcinoma BCPAP cells via disruption of intracellular calcium homeostasis. Medicine (Baltimore), 2018
  166. Hepatotoxicity induced by paclitaxel interaction with turmeric in association with a microcystin from a contaminated dietary supplement. Toxicon, 2018
  167. Curcumin dietary supplements and everolimus-based cancer treatment. Ann Oncol, 2018
  168. Chemoprevention of polyp recurrence with curcumin followed by silibinin in a case of multiple colorectal adenomas. Rev Esp Enferm Dig, 2017
  169. Sulforaphane and Epigallocatechin Gallate Restore Estrogen Receptor Expression by Modulating Epigenetic Events in the Breast Cancer Cell Line MDA-MB-231: A Systematic Review and Meta-Analysis. J Nutrigenet Nutrigenomics, 2017
  170. In vitro Biological Effects of Sulforaphane (SFN), Epigallocatechin-3-gallate (EGCG), and Curcumin on Breast Cancer Cells: A Systematic Review of the Literature. Nutr Cancer, 2017
  171. Synergistic Interplay between Curcumin and Polyphenol-Rich Foods in the Mediterranean Diet: Therapeutic Prospects for Neurofibromatosis 1 Patients. Nutrients, 2017
  172. Comparison of remicade to curcumin for the treatment of Crohn's disease: A systematic review. Complement Ther Med, 2017
  173. Curcumin for the treatment of tumor-stage mycosis fungoides. Dermatol Ther, 2017
  174. A Placebo-Controlled Double-Blinded Randomized Pilot Study of Combination Phytotherapy in Biochemically Recurrent Prostate Cancer. Prostate, 2017
  175. In vivo and in vitro effects of curcumin on head and neck carcinoma: a systematic review. J Oral Pathol Med, 2017
  176. Resveratrol in lung cancer- a systematic review. J BUON, 2016
  177. Successful treatment of c-kit-positive metastatic Adenoid Cystic Carcinoma (ACC) with a combination of curcumin plus imatinib: A case report. Complement Ther Med, 2016
  178. Intratumoral Concentrations and Effects of Orally Administered Micellar Curcuminoids in Glioblastoma Patients. Nutr Cancer, 2016
  179. Role of microRNAs in the Therapeutic Effects of Curcumin in Non-Cancer Diseases. Mol Diagn Ther, 2016
  180. Chemoprevention of hereditary colon cancers: time for new strategies. Nat Rev Gastroenterol Hepatol, 2016
  181. Research on curcumin: A meta-analysis of potentially malignant disorders. J Cancer Res Ther, 2016
  182. Targeting cancer stem-like cells using dietary-derived agents - Where are we now? Mol Nutr Food Res, 2016
  183. Curcumin downregulates human tumor necrosis factor-α levels: A systematic review and meta-analysis ofrandomized controlled trials. Pharmacol Res, 2016
  184. Phytotherapeutic interventions in the management of biochemically recurrent prostate cancer: a systematic review of randomised trials. BJU Int, 2016
  185. Effect of Curcumin Supplementation During Radiotherapy on Oxidative Status of Patients with Prostate Cancer: A Double Blinded, Randomized, Placebo-Controlled Study. Nutr Cancer, 2016
  186. An Evidence-based Approach to the Medical Management of Fibroids: A Systematic Review. Clin Obstet Gynecol, 2016
  187. NUT Midline Carcinoma: Morphoproteomic Characterization with Genomic and Therapeutic Correlates. Ann Clin Lab Sci, 2015
  188. A systematic review of dietary, nutritional, and physical activity interventions for the prevention of prostate cancer progression and mortality. Cancer Causes Control, 2015
  189. Curcumin inhibits cancer stem cell phenotypes in ex vivo models of colorectal liver metastases, and is clinically safe and tolerable in combination with FOLFOX chemotherapy. Cancer Lett, 2015
  190. Combining curcumin (C3-complex, Sabinsa) with standard care FOLFOX chemotherapy in patients with inoperable colorectal cancer (CUFOX): study protocol for a randomised control trial. Trials, 2015
  191. Safety, tolerability and pharmacokinetics of liposomal curcumin in healthy humans. Int J Clin Pharmacol Ther, 2015
  192. Effectiveness of a novel herbal agent MB-6 as a potential adjunct to 5-fluoracil-based chemotherapy in colorectal cancer. Nutr Res, 2014
  193. Topical application of a sandal wood oil and turmeric based cream prevents radiodermatitis in head and neck cancer patients undergoing external beam radiotherapy: a pilot study. Br J Radiol, 2014
  194. A double-blind, placebo-controlled randomised trial evaluating the effect of a polyphenol-rich whole food supplement on PSA progression in men with prostate cancer--the U.K. NCRN Pomi-T study. Prostate Cancer Prostatic Dis, 2014
  195. The Indian Spice Turmeric Delays and Mitigates Radiation-Induced Oral Mucositis in Patients Undergoing Treatment for Head and Neck Cancer: An Investigational Study. Integr Cancer Ther, 2014
  196. Manganese superoxide dismutase in cancer prevention. Antioxid Redox Signal, 2014
  197. Chemoprevention of skin melanoma: facts and myths. Melanoma Res, 2013
  198. Curcumin for radiation dermatitis: a randomized, double-blind, placebo-controlled clinical trial of thirty breast cancer patients. Radiat Res, 2013
  199. Topical curcumin for the prevention of oral mucositis in pediatric patients: case series. Altern Ther Health Med, 2013
  200. Advances in prostate cancer chemoprevention: a translational perspective. Nutr Cancer, 2013
  201. Differential androgen deprivation therapies with anti-androgens casodex/bicalutamide or MDV3100/Enzalutamide versus anti-androgen receptor ASC-J9(R) Lead to promotion versus suppression of prostate cancer metastasis. J Biol Chem, 2013
  202. A phase I study investigating the safety and pharmacokinetics of highly bioavailable curcumin (Theracurmin) in cancer patients. Cancer Chemother Pharmacol, 2013
  203. Prolonged biologically active colonic tissue levels of curcumin achieved after oral administration--a clinical pilot study including assessment of patient acceptability. Cancer Prev Res (Phila), 2013
  204. Preliminary experience with personalized and targeted therapy for pediatric brain tumors. Pediatr Blood Cancer, 2012
  205. Effect of imatinib therapy with and without turmeric powder on nitric oxide levels in chronic myeloid leukemia. J Oncol Pharm Pract, 2012
  206. Upregulation of p53 expression in patients with colorectal cancer by administration of curcumin. Cancer Invest, 2011
  207. A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer. Cancer Chemother Pharmacol, 2011
  208. Potential response to curcumin in infantile hemangioendothelioma of the liver. Pediatr Blood Cancer, 2010
  209. A systematic review of topical treatments to control the odor of malignant fungating wounds. J Pain Symptom Manage, 2010
  210. Combined inhibitory effects of soy isoflavones and curcumin on the production of prostate-specific antigen. Prostate, 2010
  211. Critical need for clinical trials: an example of a pilot human intervention trial of a mixture of natural agents protecting lymphocytes against TNF-alpha induced activation of NF-kappaB. Pharm Res, 2010
  212. Phase I dose escalation trial of docetaxel plus curcumin in patients with advanced and metastatic breast cancer. Cancer Biol Ther, 2010
  213. Bortezomib successfully reverses early recurrence of light-chain deposition disease in a renal allograft: a case report. Transplant Proc, 2009
  214. Bioactive compounds: historical perspectives, opportunities, and challenges. J Agric Food Chem, 2009
  215. Curcumin has bright prospects for the treatment of inflammatory bowel disease. Curr Pharm Des, 2009
  216. Liver metastases after colonic carcinoma--palliative chemotherapy plus curcumin. Int J Colorectal Dis, 2009
  217. Green tea polyphenols in the prevention of colon cancer. Front Biosci, 2007
  218. Preclinical assessment of curcumin as a potential therapy for B-CLL. Am J Hematol, 2007
  219. Antimicrobials, mucosal coating agents, anesthetics, analgesics, and nutritional supplements for alimentary tract mucositis. Support Care Cancer, 2006
  220. Dose escalation of a curcuminoid formulation. BMC Complement Altern Med, 2006
  221. Targeting angiogenesis with integrative cancer therapies. Integr Cancer Ther, 2006
  222. Curcumin, an atoxic antioxidant and natural NFkappaB, cyclooxygenase-2, lipooxygenase, and inducible nitric oxide synthase inhibitor: a shield against acute and chronic diseases. JPEN J Parenter Enteral Nutr, 2006
  223. Consumption of the putative chemopreventive agent curcumin by cancer patients: assessment of curcumin levels in the colorectum and their pharmacodynamic consequences. Cancer Epidemiol Biomarkers Prev, 2005
  224. Phase I clinical trial of oral curcumin: biomarkers of systemic activity and compliance. Clin Cancer Res, 2004
  225. Early human safety study of turmeric oil (Curcuma longa oil) administered orally in healthy volunteers. J Assoc Physicians India, 2003
  226. Point: From animal models to prevention of colon cancer. Systematic review of chemoprevention in min mice and choice of the model system. Cancer Epidemiol Biomarkers Prev, 2003
  227. Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa). J Altern Complement Med, 2003
  228. Cancer chemoprevention by dietary constituents: a tale of failure and promise. Lancet Oncol, 2001
  229. Clinical development of leukocyte cyclooxygenase 2 activity as a systemic biomarker for cancer chemopreventive agents. Cancer Epidemiol Biomarkers Prev, 2001
  230. Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions. Anticancer Res, 2001
  231. Pharmacodynamic and pharmacokinetic study of oral Curcuma extract in patients with colorectal cancer. Clin Cancer Res, 2001

Other conditions Turmeric has been studied for

Checked against PubMed on 2026-10-28. Everything we know about Turmeric